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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd587e4fe476b33fcee022c8811138123a3f1318c9a9d974652f587b22f799f7d' 
  AND token = 'VE02odWcmuaURjIjTbLvT/OeciVB0fDCEbf7JTeR/xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}