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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ab5bf1c47da0fa157b3522b2aee2bda99e7320b40f7c38b1076723611ef1a2' 
  AND token = 'pkGHYuSy9/DzcxblymxaFhXA4hl9YRiIbErSBl/Nt9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}