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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb6ee600fa27b5968f18a4d8714878e75e2a2ec514c7905033904196c5a3b49' 
  AND token = 'v2eZZALhjDmdy6bvwAiTSEobWTfUAWAhbFCfK8T0Vt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}