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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3ce15ecde96d7a80c800e6a79b250b11415ee1c5fb007b17e5953137317160' 
  AND token = '/Y9DUELPq4bgKLgZAYwm2lk07sn2QteVqG93iD6tRJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}