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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16def32624ea8bf497bc5c4b80c6add9f2ef34ca31ff7400a0d99f9f2e0a660' 
  AND token = 'sMHwm5AphQlV0hr9nOqAG9AMA7MPwSie+Cmi21Kib8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}