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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c85401abc3e1e67eaacb5a148987cccbd00a49127e46bcc1d30643b73d72d056' 
  AND token = 'jxtwLL2VbI34jo/WN0h/lkiRqwKkaFG+dpU32VY9vYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}