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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2c3ecac2e8638e8ca4fc91c7b65637bcbc0dec3f434528324d0431643994f2' 
  AND token = 'gsqWIQ0BuLY76QdNwjkL/LGar6+uGRhxJO46yEX8wG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}