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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491760777f6d960b2dd16b8157e476466d712a2843b754a54150a488ba81bd97' 
  AND token = 'pS7wg9zfODk1ZoCmhhhPYr+06bBv21rMN3rbDzG9Czc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}