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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa2d1f993442f70e300dd7b1323532cc53004f972a26773d007b451a51535a64' 
  AND token = 'iR26TheBIpZp1v8B5tYGNPfwarKQdF55zLqyxffhXw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}