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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a27dd267c0a6a4c51f02d016ee58d6a06e443a4f84a2d9bc3c48e0104292750' 
  AND token = 'wXfsdH9lwlkXFn97RZYBPsiUrFhcabl4ZaE9fD/cZW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}