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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c549e1b2c1d3fa109da4412251c0e9a3d7ba5f79a401c22145eff20ddca6c489' 
  AND token = 'GVYrNR6uli3xsAZeH5GNN4SeBiFz8b5b9ZAUX4qcvu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}