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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd244473daf39ac24cad8b494513a163ae6fb0715acc1c5cc13281a5f2cfdfeab' 
  AND token = 'DTF6RZgyL4IffYCZqYGdNQ834DqIswTIjas2XZWtaSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}