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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1170da26625868f16fb5a0ac7d537f3d5922128cb657b3088439b4e6e7f7910' 
  AND token = 'JfDL7WnY2cj/pvny4irt01WeIRF5ZTiu54ICyXZe7Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}