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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef5f6a1833bdc02fed57e3dcd4d6c058ab36ed0ab384e7b3355fd849fa700ad' 
  AND token = 'M+nrvy39mairzH1/v/LcOTek+j+LEK9tvYRMrSTRjPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}