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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd51f005930016ed5321552e8173a87a5a710f948e1cd42ea2801e86e0879de08' 
  AND token = 'TAZS1hSSOvFXqe/9XnQU3NJb1p81JBa/mRSisYQZIXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}