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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b57a115bc32b6b7e5363644ba52b899f4b97d2c5c4c9e080f0d4bb424a22b8b' 
  AND token = 't8LiovyTWOuS5QpMRhfcV7GErAJBHZ0rkbeyUHEZYMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}