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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '432ebf563f56d6453cb464f397851f777451be8bb2fdc038053066e06a11302a' 
  AND token = 'AcT8b/UwV7j/vDe2BB4e7DWKtxZp20GIgKnAvEpXAuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}