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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3720c81baeef66127bae730335b59379a845c87e1f9c92d8f7db7be4b0f3af34' 
  AND token = 'nCE11LxIZYnumN2/2sG3GTg9PavDP0P7kWbfW+I2dlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}