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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c273faab26843b046f2d0aec9ca2fa3b2962d85eea803b7ddadf9e122d73c086' 
  AND token = 'zX8pGAXKrc+GSKhQxSkaHMc5uc4KYlZiXZmkeswYiZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}