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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd59d764baffa2764fe019b44fd1002637318609e5f6845c1ccd1e60f9b260cb' 
  AND token = 'k6Vet+Q6uCYyqLg32SwyRDHT2JvfbQ6wwc13q+Tsr1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}