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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '039a18d051576f20094486ccb0792c1d13174f4e8789ea029558a840ce20c6d0' 
  AND token = '/FbZotui/a7eOIx9LSXdRVR2Caey42ojK8csvMAjkqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}