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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4ee1995c5d2e0051b49fe87fe949027b709ea3a0cc18847b6c029bc550a4434' 
  AND token = 'tLEC8gs+0OxWkU9EfFiOmThGnHVoQjE0kgLjgJ4O2dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}