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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678c9bc9ec916f0335d184290eb5b91fa5a2e66e4a75719bc705c08db2164e99' 
  AND token = 'BCbfPcbnFBMKCMxnSiBz7vkZGo5gFWJG3jUcVA0IjE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}