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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '252109b04344cb9f23727947402398d5fb6d02cd8641818c11ce97bc176ad314' 
  AND token = 'Jt2C6eBYynNqLlnluLhPlkbF6P16si8cd5xvafYGkzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}