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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6118e0eba6b7cc2b191aa2cef69136dfdd83aa6067441487e98055615cab177b' 
  AND token = '+C4EvRVYYNdLnwCyZbFJvAiaLxMHAyfZECiPPtW9lGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}