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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1475a6d034647a068dedfbde447d89a2879a1bd67ceb41dade0b3eaf9f88d8a9' 
  AND token = 'ISImnhPA+jADY6PoeJ5Phz0zUG1y1SKuVArbUy09TL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}