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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9451e2235199f41f17abae9aeabd9ad9a3a27d6e81eb9eb0e5a7a3e334c92ac9' 
  AND token = 'DXGKq8cRlT2Jy1NqfhD+HR5qNI63RQzhDW26FFYNbpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}