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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45da5b7325c2f644988e10bd0202094c1f35c4f5e1dc5683ebdb9ccc106ac8d' 
  AND token = 'IwcOeE/naVAEU5G0tQ0ROkJqvyeaQzV4P/VIaLzs07U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}