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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57491320c593e4f787c0bce47c1fdc54f9826af66c6fe6a956a815f13fdd562d' 
  AND token = 'gcu4cx3UN7ZR39BboNYbxt4TRaijG3YRDObUq1f2FFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}