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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159b3378f3929c4cc6485bca092ccdbf7892e301e03e0fdc5badccbe1146bd48' 
  AND token = '15AkR6M6jRXW40IcGpVP8qNqJvfaDHfUgv1cj6vFH7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}