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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d5139807ba9c46d9cfe6567d3430548408ce47a26098ee67eb8b9720a2ad576' 
  AND token = 'T4ZTe1cPq6zvRVDTAK8jLJDtyilCP4JKADoDRjhgh1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}