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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d28429654f5b5c04dcf13ede3cef5f3442f455e7dc89bcd405074e2d1b5937' 
  AND token = 'GSTn0kfmxzpctiBaTTGUvqv1wOTYLjsXbYP1Ba6zqqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}