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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7743877b6bac1b34cddb2786dbd20506c03473c83023082888669ce236dbea73' 
  AND token = 'o8YAApCrdKJpDT0JCabPr5+AjBZvvaTDGUZtP3k20ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}