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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d8560d01bee25e7a1e29442af5506369824b224b0be1b18295c1c51fb8121b' 
  AND token = 'QKFDt03439UYOeUk1uPW9tr7bp9xJhZSO9TtLAUDtYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}