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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490b9ccc394be87dda37f7832a03bb89fd180d39e7eb6456544f0f15ad66b2ed' 
  AND token = '6VqulrBYUTK06w4THdeN+DWQu7Unn1QKtHPpZTwipWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}