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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4a0a80df56247f8e380d8d0df4b29da1e08b04bfb72d2c3db00e47d66954d0' 
  AND token = '5G59UnoKKLRpqtvNnCNBJq3b40CH8UyQm6ssV8QbwkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}