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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa9723019e47c3d5ae917a096bbdd8833c210b8636cd5e491a6942e9006888f' 
  AND token = 'UroTpAuGqk3Ym2qCuGzMN933qaVFrqADgIN+3s1uhFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}