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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a01cf2e680f29971a1d1e5992555d7c3e3cdb15c31314fa9334668ae64c9e7' 
  AND token = 'AGF5hXFBpJ1/icpWhTq5IgYwb89oTL4TE2EleGUtTp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}