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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35280e059d0b1302d17eebf50f643d4c3b8e056f0ac25e1dba314c3b50ce33c4' 
  AND token = 'Vr692qbszhO+QzAsy+DAmBaL+FUqc7/4w4FlqLKRqiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}