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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cf44fd7a9a834e926fcd9d986eb5a7957cb93e1c0e682b89434d66ebc8ca93' 
  AND token = 'VWWKI7T+BlVsHtDonsY74kq+lqYDNMXYYPobOqErEao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}