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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493c4b8e6004c273834e59053b17b0ab46a6f35dc71827ded79aa7f3f2ff3e03' 
  AND token = 'RzoM5F15Nwz5FZTdlXD6wq4CvtkI+5vQJ/tc87t2rtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}