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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4401bcf705444bf46b72f756be9acf47ac1ea8c0d596b8635ee47cb1ff904e18' 
  AND token = '0T0Q/WFn3I6yKQyqOB1iBYcPEiSvOHXFDMQLLGpv5Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}