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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b93b296aa4f15e159a857802e969c97f8426c2f51d2e97da883ddf7d5c080d14' 
  AND token = 'Mu9GJl/PYx1F3FdQ/MET4Os3RJONwlyjf6dC5Im2XOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}