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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b2f61b460afa6c5769d33ad48e89b1910d9e35a193ac36f89cf0a2eb8b8a94' 
  AND token = 'zOBTKW8Lejq4GQ6pbV9bDzPxEC+CTF8BRBvjSSAubk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}