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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78bb3481cec46206bdc322cf2a02b266d9b7604b9c903b224ec429aaa131e42' 
  AND token = '5d/dMYPrpxM4akOE7IqesKirl3H+lU2VrnXr1naaa7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}