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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '194622bf4d93af145f8c44133b3109bd30fcbac536e5965d4bd5b396eb002d01' 
  AND token = '1b+v8e5rxypNsy224k5bZUt3F6anqFHgXcExb4saIAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}