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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d148dfdfddf3bce6725d2616af57efa99a775774b5deb1a7a8253323ac6b51' 
  AND token = 'LZRqf8WEgEHZ8N5Ml4A6xKWl8BLtK0EGRhGIT2dBSUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}