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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e50b2d6196f32739b883f87ba2e92c124df83e219c176171bac0a01ab6beaf7' 
  AND token = 'oLD5RIH8Xrhk1BHPfbNZP9UwLbLj70OT4kY/7CqQwVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}