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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68c83bdc19f1c7da6a3f797a0abca8c97a61cab89d81a23cd0db87f2f733735' 
  AND token = 'igplz+4XaTFONvbIKGp/JdREFS5N8Ui8ph/GuQG6bmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}