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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a288c51b322432a671a6888e182044b80783dc41002f0f74b463ac06ce3cf22' 
  AND token = 'M19FIYwJe7cu6q8EMyzcyxoxr6WAjA149PF1rkIeJmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}